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br Materials and Methods br Results
2022-08-29
Materials and Methods Results Discussion A model of seizure and excitotoxicity induced by neonatal MSG administration was described recently (19) in which extracellular glutamate increased after the first and second MSG administrations were observed, the greatest increase seen following the
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Although it is mainly a glial protein of
2022-08-29
Although it is mainly a glial protein, 5–10% of total GLT-1 represents a neuronal form located at presynaptic terminals, but its physiological role remains elusive (for discussion, see (Rimmele and Rosenberg, 2016)). Nevertheless, this amount might be significant since GLT-1 has been estimated to be
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Moreover to evaluate the properties of immobilized glucosida
2022-08-29
Moreover, to evaluate the properties of immobilized β-glucosidase further, the anti-protease test was also carried out. The result showed that the residual activity of the β-glucosidase@ZIF-8 was higher than that of the nano-SiO2@β-glucosidase and free β-glucosidase. Because free β-glucosidase and t
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As many of the above studies highlight several decades
2022-08-29
As many of the above studies highlight, several decades of research on Cx43 has revealed that many of these functional roles are attributed to the C-terminal domain (CT) of this protein which cannot be explained by the formation and existence of intercellular channels. Recent findings on the existen
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The gene structures of cGalR and cGalR
2022-08-29
The gene structures of cGalR2 and cGalR2-L were determined by in silico comparison with the chicken genomic DNA sequences retrieved from the Ensembl database. Both cGalR2 and cGalR2-L genes are composed of two coding exons, separated by single introns of 0.9kb (cGalR2) or 3kb (cGalR2-L) locating wit
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br Acknowledgements Funding for this study is
2022-08-29
Acknowledgements Funding for this study is gratefully acknowledged from the Department of Employment and Learning (QC) and the Northern Ireland Chest Heart and Stroke Association (2008107). Introduction Preeclampsia is a major human pregnancy-specific disorder that occurs in at least 5–10% of
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1-NM-PP1 synthesis The progression of HIV varies from
2022-08-26
The progression of HIV varies from patient to patient, with some who progress slowly and others who progress much faster. However, CD4+ and CD8+ cell counts are intimately linked in those that are able to suppress the HIV infection (Walker et al., 1986; Saez-Aninon et al., 2007). Depletion of these
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br Introduction Ovarian cancer patients
2022-08-26
Introduction Ovarian cancer patients have the highest mortality rate amongst patients with gynecologic cancers. The 10-year survival rate of ovarian cancer patients is verubecestat with BRCA1/2 mutation [2]. Several studies have indicated the role of dysregulation of histone methylation in carc
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br Conclusions Histone acetylation deacetylation is a major
2022-08-26
Conclusions Histone acetylation/deacetylation is a major epigenetic mechanism implicated in the regulation of transcription and various biological processes such as development and gametogenesis from plants to vertebrates. However, despite being well characterized in zebrafish, acetyltransferase
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Although HK localizes mainly to either
2022-08-26
Although HK localizes mainly to either the cytosol or mitochondria [29], [30], [31] and cardioprotection is associated with increased mitochondrial HK binding, some studies have identified a component of HK located in intracellular vesicles within the cardiomyocyte [48], [61], supporting older data
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CD CD belong to the
2022-08-26
CD80/CD86 belong to the costimulatory adhesion molecule family, which can activate T 449 receptor by the costimulatory pathway and have been used as indicators of DC maturation in numerous studies. In addition, MHC-II, as the principal component of antigen presentation, was significantly elevated a
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br Material and methods br Results br Discussion In
2022-08-26
Material and methods Results Discussion In this paper, an HCV molecular epidemiological study was conducted in DU sentinel surveillance sites in 20 prefecture-level cities across Guangdong Province, and the different subtype distributions between IDU and NIDU were compared. Owing to the lac
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br Concluding Remarks and Future Perspectives Our understand
2022-08-26
Concluding Remarks and Future Perspectives Our understanding of substrate targeting mechanisms utilized by kinases has grown tremendously in the past few years, but challenges still remain in relating these mechanisms to the organization of complex signaling networks. Substrate prediction based o
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Similar to Rac Cdc and
2022-08-26
Similar to Rac1, Cdc42, and RhoA, expression of Rnd3 is also increased under hypoxic conditions, involving Hif1α mediated transcriptional activity. Here, downregulation of Rnd3 abolishes hypoxia-induced cell migration via a mechanism involving the chemokine receptor C-X-C motif chemokine receptor 4
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br Conclusion GST expression was
2022-08-26
Conclusion GST expression was detected in the Hemicornea construct and the commonly used animal cornea models at both the protein and functional levels. The results are summarized in Table 1. However, the construct exhibited lower levels of activity of GST, a marker of phase II enzymatic activity
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