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Accordingly blockade of TL A Fas L TLR cascades
2019-05-24
Accordingly, blockade of TL1A/Fas-L/TLR4 cascades and inhibition of the M1/Th1 differentiation associated with DcR3 might potentially rescue hepatic IR injury. However, the contribution of TL1A/Fas-L/TLR4 on the M1/M2 and Th1/Th2 balances, as well as pathogenic liver IR injury had never previously b
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br Among the most important findings to
2019-05-23
Among the most important findings to have emerged from the massive 2013–16 outbreak of Ebola virus disease in west Africa is the delayed clearance of virus from the semen of men who survived the disease and the consequent risk of sexual transmission of the virus, although this seems to be rare. In
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br Uganda is on the verge of eliminating
2019-05-23
Uganda is on the verge of eliminating the () form of human African trypanosomiasis (HAT), commonly known as sleeping sickness. This elimination would be historic. In 2015, only four cases of this neglected tropical disease were diagnosed in the entire country. A similarly low number of cases in 2
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Furthermore many potential risk factors were examined in the
2019-05-23
Furthermore, many potential risk factors were examined in the current study, which contained a broad array of factors. Based on such a classification, groups of some factors were earlier referenced in the literature. Although the distribution of association between some risk factors and SRH were sim
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This trial included patients who met the
2019-05-23
This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170
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En Introducci n Bases filos ficas del poema Evodio Escalante
2019-05-23
En “Introducción. Bases filosóficas del poema” (11-34), Evodio Escalante une los tres hilos de las grandes madejas que considera fundamentales para entender el origen y los alcances de este poema filosófico: Heidegger, Nietzsche y de Gorostiza. La presentación es gradual y va de la mera conexión an
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Funding secured by Not applicable Data
2019-05-23
Funding secured by: Not applicable. Data collection: Sheldon M. Singh, MD, Ramanan Kumareswaran, MD. Conflict of interest Acknowledgments Introduction Early repolarization pattern (ERP) is characterized by an elevation greater than 0.1mV of the junction between the end of the QRS complex
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br Case report A year old patient
2019-05-23
Case report A 38-year-old patient with pectus excavatum received a dual chamber ICD after resuscitated cardiac arrest due to ventricular fibrillation during myocardial infarction following vasculitis (Fig. 1, Panel A). He developed fever and chill after the ICD implantation, consistent with the g
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hiv protease inhibitor We are in the midst of
2019-05-23
We are in the midst of a paradigm shift for antenatal and intrapartum care: from focusing mainly on coverage to also considering quality as an essential component of improving health systems, as stated in the WHO vision on quality of care and other efforts. For intrapartum care, poor quality at faci
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UNC 0642 Comparative data on the clinical
2019-05-22
Comparative data on the clinical presentation and outcome in NmC and NmA are scarce. In a brief report from northern Nigeria in 1977, 114 patients with meningococcal infection were studied, of whom 72 patients had NmC infection and 42 patients had NmA infection. All patients who UNC 0642 had bacter
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estrogen related receptor Introduction Despite advances in b
2019-05-22
Introduction Despite advances in breast cancer treatment, bone remains the most common site of estrogen related receptor [1,2] occurring in around 70% of patients with metastatic disease [3]. Bone metastases are incurable and associated with significant morbidity in terms of fractures, pain, and r
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br Discussion There were recurrences out
2019-05-22
Discussion There were 2 recurrences (8.3%¸ 2 out of 24 patients), 1 of which occurred immediately following the procedure. In this patient, SVT was not induced with programmed atrial or ventricular stimulations after the ablation of accessory pathway. Ventriculoatrial conduction was through the A
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Education and lifestyle changes for
2019-05-22
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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br Epigenetic regulation of genes involved in hepatic lipid
2019-05-22
Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl
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In their analysis the investigators did not include
2019-05-22
In their analysis, the investigators did not include common causes of CKD in sub-Saharan Africa other than HIV, diabetes, and hypertension—notable omissions were chronic glomerulonephritis and use of herbal or traditional treatments. Also, communicable diseases might contribute substantially to CKD
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