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SCR 7 Finally MM patients have accelerated bone loss when
2019-05-10
Finally, MM patients have accelerated bone loss when compared to age-matched controls. Bone mineral density is decreased in patients with MM as well as in patients with monoclonal gammopathy of undetermined significance (MGUS) [19,20], a clinically benign condition defined by a low level of monoclon
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PROFACE aimed to investigate the efficacy
2019-05-10
PROFACE aimed to investigate the efficacy of atorvastatin in preventing POAF and SIRS. Atorvastatin, 40mg/day, was administered 7 days before and after elective HG-9-91-01 valve surgery in a randomized patient population with no preoperative beta-blocker treatment or previous episodes of AF. The ju
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Acknowledgement br Introduction Pulmonary veins PVs have bee
2019-05-10
Acknowledgement Introduction Pulmonary veins (PVs) have been reported to be the major site of ectopic foci initiating paroxysmal atrial fibrillation (AF) [1]. Pulmonary vein isolation (PVI) is an established therapy eliminating those foci [2,3]. Non-PV ectopic foci from the superior vena cava (S
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br In Gretchen Stevens and
2019-05-10
In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affect
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Using the finding of a reduction in neonatal mortality
2019-05-10
Using the finding of a 12% reduction in neonatal mortality, Pitt and colleagues show that, even though the reduction in neonatal mortality was relatively modest, the intervention would still be cost-effective. With further statistical modelling they calculate that such an intervention is likely to b
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br Conclusion br Conflict of interest br
2019-05-10
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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br Conclusions br Study limitations
2019-05-10
Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum h
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HBTU Roux en Y gastric bypass surgery is a
2019-05-10
Roux-en-Y gastric bypass surgery is a common cause of malabsorption associated with hyperoxaluria in obese patients and those with malignancies. Postoperatively, patients may have steatorrhea, weight loss, and diarrhea, resulting in malabsorption syndrome, which would increase excessive intraluminal
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Cardiovascular magnetic resonance imaging CMR is recognized
2019-05-09
Cardiovascular magnetic resonance imaging (CMR) is recognized as a versatile, safe, and reproducible technique, allowing for accurate structural and functional assessment of the heart. CMR is the gold standard for ejection fraction measurement [15–17]. Considering the technical limitations of other
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La descripci n arquitect nica de
2019-05-09
La descripción arquitectónica de la quinta es heterogénea, extensa, precisa, sugerente, sin duda uno de los pasajes en El fistol del diablo más revisados y pulidos por Payno, con la totalidad de la novela en mente, por lo tanto pleno de simbolismo histórico-cultural y de presagios. Por principio, el
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To date only one study regarding the role of
2019-05-09
To date, only one study regarding the role of miRNAs during hepatic cyst formation has been published. While this is an older publication, published in 2008, the findings are worth discussing, based on the limited information on miRNAs during PLD. In whole liver sections from patients with PLD due t
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Immediate rollout of an effective and safe
2019-05-09
Immediate rollout of an effective and safe short-course treatment regimen is essential for the attack phase of the visceral leishmaniasis elimination programme, which aims to reduce the incidence to less than one case per 10 000 Zalcitabine at risk. A single-dose liposomal amphotericin B regimen, w
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br Conclusion br Conflict of interest br
2019-05-09
Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electric
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Introduction Personalized medicine is the major goal of tran
2019-05-09
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease RG7388 and predict clinical outcome. However, to define a specific disease phenotype, it
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Funding secured by Not applicable Data collection Sheldon M
2019-05-09
Funding secured by: Not applicable. Data collection: Sheldon M. Singh, MD, Ramanan Kumareswaran, MD. Conflict of interest Acknowledgments Introduction Early repolarization pattern (ERP) is characterized by an elevation greater than 0.1mV of the junction between the end of the QRS complex
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