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In conclusion the current study presents solid evidence show
2019-04-29
In conclusion, the current study presents solid evidence showing the hepatic oxidative stress and damage, along with lipid accumulation, inflammation, ER stress and its associated cell death, fibrotic responses, and consequently hepatic dysfunctions in TAA-treated rats. It also demonstrated that sup
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br Materials and methods Fifteen patients were
2019-04-28
Materials and methods Fifteen patients were included in the study (age, 48±13 years; nine men). Six patients underwent ablation of accessory pathways, while the other nine had atrioventricular nodal reentrant tachycardia and underwent slow pathway ablation. A quadripolar catheter in the right atr
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Recently genetic analysis in mice
2019-04-28
Recently, genetic analysis in mice supports the candidacy of the G protein-coupled receptor 30 (GPR30), a novel estrogen receptor, for a new gallstone gene Lith18. Of special note is that ∼50% of cholesterol is converted to bile acids in the liver each day in humans and in mice. Because GPR30 is loc
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For many decades scientists have
2019-04-28
For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug
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br Remote technologies The platforms available for remote mo
2019-04-28
Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c
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br Discussion ATS is rare and there are
2019-04-28
Discussion ATS is rare, and there are few reports of pregnant patients with this condition. Subbiah et al. [6] reported a case of pregnancy complicated with ATS in which ventricular ectopy was also decreased during pregnancy. The mechanism underlying the reduction of VA in pregnant patients with
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br Quentin Eichbaum and colleagues
2019-04-28
Quentin Eichbaum and colleagues describe how new medical schools in Africa have developed curricula that include community and rural health components, long-term family attachments, and admission processes that are more equitable for disadvantaged students. All these worthwhile innovations have be
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Las colaboraciones de Woinoff conforman el
2019-04-28
Las colaboraciones de “Woinoff ” conforman el último vértice de la constelación intelectual que, ion channels nuestro juicio, pudo haber ayudado en el cambio intelectual de Bilbao. En ellas, el pretendido “atraso” se vuelve reserva moral desde la cual la democracia radical europea puede pensar de ma
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br We have concerns about both the accuracy
2019-04-26
We have concerns about both the accuracy and underlying rationale of Eugene Richardson and colleagues\' Comment about the “Ebola suspect\'s dilemma”. The authors quote a nosocomial infection rate of “around 25%” for individuals admitted to Ebola treatment facilities without Ebola virus disease. Ho
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On what might an argument for
2019-04-26
On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater
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Introduction Atrial fibrillation AF is a highly prevalent at
2019-04-26
Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF
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br Diagnostic criteria Brugada syndrome is definitively diag
2019-04-26
Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s
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br Introduction Sudden cardiac death SCD in patients with
2019-04-26
Introduction Sudden cardiac death (SCD) in patients with low ventricular function remains a substantial problem despite improved medical therapies [1–3]. Many patients require antiarrhythmic drugs to prevent recurrent arrhythmias and reduce the number of shocks from implanted cardioverter-defibri
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Introduction Dilated phase hypertrophic cardiomyopathy DHCM
2019-04-26
Introduction Dilated-phase hypertrophic cardiomyopathy (DHCM) is a rare subset of hypertrophic cardiomyopathy (HCM) [1]. Data available on sustained monomorphic ventricular tachycardia (SMVT) associated with DHCM is scarce. We report a rare case of SMVT caused by a large epicardial scar related to
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Juan Tovar dramaturgo y cr tico teatral presenta en
2019-04-26
Juan Tovar, dramaturgo y crítico teatral presenta en su texto “Los siete géneros”, la teoría que aprendió durante su paso por las aulas de la maestra Luisa Josefina Hernández y cuyas lecciones no obstante su continuo estudio y aplicación por directores y actores en talleres y escuelas de teatro, no
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