• br Funding This research was supported by a grant from

  2018-11-07

  

  Funding This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI14C1731) and funded by the Ministry of Education, Science and

• Mechanistically the age promoting effects

  2018-11-07

  

  Mechanistically, the age-promoting effects of senescence are associated with the restriction of regenerative capacity of stem and progenitor thrombin inhibitors (Choudhury et al., 2007; Jurk et al., 2014) as well as the secretion of bioactive molecules (the so-called SASP (Coppe et al., 2008)), spe

• Intramuscular IM oxytocin international units IU was identif

  2018-11-07

  

  Intramuscular (IM) Aminoallyl-dCTP - Cy3 (10 international units [IU]) was identified as one of 13 life-saving commodities for women and children in a 2012 United Nations (UN) Commission Report (United Nations, 2012), and was included in the World Health Organization (WHO) model list of essential me

• br Data experimental design materials and methods

  2018-11-07

  

  Data, experimental design, materials and methods Specifications table Value of the data Data Mean peak values obtained from intact glucose assay (IC), detergent-soluble extracts (SD) and detergent-insoluble extracts (ID) associated with immature (IC2, SD2, ID2) and mature epididymal sper

• Specifications table br Value of

  2018-11-07

  

  Specifications table Value of data 1. Experimental design, materials and methods 2. Direct link to deposited data Deposited data can be found here: http://www.ncbi.nlm.nih.gov.eleen.top/GBRH01000000. 3. Nucleotide sequence accession number The assembled and annotated A. donax USA p-gp

• br Specifications table br Value

  2018-11-07

  

  Specifications table Value of the data Data Experimental design, materials and methods Fractionation of human plasma samples Frozen human plasma samples from healthy volunteers were obtained from expired stocks of local blood banks, pooled and fractionated by anion exchange chromatogr

• Data experimental design materials and methods

  2018-11-07

  

  Data, experimental design, materials and methods Conflict of interest Acknowledgements We would like to acknowledge the BBSRC for support (grant BB/H001948/1), the Chemical Analysis Facility at the University of Reading for access to the Orbitrap instrument, the Centre for Advanced Microscopy

• Considering developmental aspects children may have had more

  2018-11-07

  

  Considering developmental aspects, children may have had more difficulties to implement reappraisal as adults, constricting their ability to stay on task during the whole block. Moreover, during childhood, cognitive control-related PFC activity is known to undergo substantial developmental changes (

• The current results are consistent with the animal

  2018-11-07

  

  The current results are consistent with the animal models of cannabinoid exposure during adolescence (Rubino et al., 2008; Schramm-Sapyta et al., 2007) and suggest that more human research is needed on the long-term effects of cannabis use in adolescence. In consideration of the animal studies and t

• Researchers have previously examined how hormonal changes

  2018-11-07

  

  Researchers have previously examined how hormonal changes related to pubertal development coincide with changes in alcohol consumption. Puberty onset starts approximately around age 9–10, although on average about 1.5 years earlier for girls than for boys, and it is marked by changes in both hormone

• natriuretic peptide receptor This view of ventral striatum s

  2018-11-07

  

  This view of ventral striatum sensitivity as being adaptive and directing adolescents away from health-compromising behaviors has significant implications for the development of effective treatment and intervention efforts to prevent upward trajectories of depression, risk-taking behavior, and subse

• jnk pathway This association between cortical folding

  2018-11-07

  

  This association between cortical folding and network functioning may mediate relationships between early sulcal patterns and later functional development (Mangin et al., 2010, for review). For example, we recently showed in a longitudinal study in preschoolers (Borst et al., 2014) that the ACC sulc

• Findings are relevant to both intervention targets

  2018-11-07

  

  Findings are relevant to both intervention targets (e.g., personalized medicine) and intervention mechanisms. For example, an emerging literature suggests that targeted interventions remediating attentional vigilance (‘ABM’ procedures) have a broad impact on clinical anxiety symptoms (Hakamata et al

• The difficulties in defining interoception are reflected in

  2018-11-07

  

  The difficulties in defining interoception are reflected in its characterisation and measurement. For example, it has been suggested that individual differences in interoceptive ability should be considered on three dimensions rather than one: objective interoceptive sensitivity (the degree to which

• In the present work we focus on augmented reality

  2018-11-06

  

  In the present work, we focus on augmented reality (AR), which can super-impose a present surrounding landscape acquired with a video camera and 3DCG (Milgram and Kishino, 1994; Azuma, 1997). The use of AR involves the inclusion of a landscape assessment object in the present surroundings. In this a

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