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br Conclusion Pu erh extracts showed a
2018-11-12
Conclusion Pu-erh extracts showed a strong protection effect against the hepatic damage by oxidative stress. The protection mechanism of Pu-erh extracts is confirmed in the study via the activation of the hepatic antioxidant system and the reversal of lipid peroxidation. In addition, Pu-erh tea e
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Results br Discussion In this study we
2018-11-12
Results Discussion In this study, we described the differentiation of hiPSCs into efficient functional ECs and compared them with hESC-ECs. We have found that hiPSCs, similar to hESCs, can be differentiated into ECs by the use of a sequential combination of FLK1-positive (EPC marker) and CD31-po
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glucose transport proteins In cardiac hypertrophy associated
2018-11-12
In cardiac hypertrophy associated with pathological processes, it has been shown that CSCs participate in the reparative processes (Ellison et al., 2013; Leri et al., 2005); however, extensive damage cannot be completely reversed, indicating that the regenerative potential of these stem glucose tran
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To investigate apoptotic and necrotic
2018-11-12
To investigate apoptotic and necrotic cell death, we have used a phosphatidylserine-binding protein (Annexin-V-FITC) to detect apoptosis-dependent redistribution of phospholipid. Cells were also counter-stained with PI to distinguish apoptosis from necrosis. We found few apoptotic and necrotic HOBt
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br Acknowledgments We thank members of the Morshead van der
2018-11-09
Acknowledgments We thank members of the Morshead, van der Kooy, and Shoichet groups for helpful discussion. Anand Swaroop kindly provided the Nrl.gfp mouse strain, and Samer Hattar kindly provided TKO mice. We thank Samantha Yammine, Vincent Huynh, and Shannon Sproul for assistance with behaviora
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IL IL E is a member of
2018-11-09
IL-25 (IL-17E) is a member of the IL-17 family (Iwakura et al., 2011). However, unlike IL-17A or F, the better-known members of this IL family that have direct roles in autoimmune and chronic inflammatory diseases, IL-25 actually appears to protect against IL-17A/Th17 and Th1 states (Caruso et al.,
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br When the hypothesis is true the distribution of a
2018-11-09
When the cannabinoid receptor Н∗ is true, the distribution of a quantity asymptotically approaches the χ-squared quantity with k degrees of freedom with an increase in sample size n, i.e. . Let us assume that the parameter vector is tested by the linear regression method: where Y is a column v
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To assess the stability of the dSe
2018-11-09
To assess the stability of the СdSe/l-Cys quantum dots in buffer solutions we conducted experiments where QDs in a concentration of 17.5 μM/ml were added to the following solutions: a phosphate-buffered saline, pH = 7.5 (BIOLOT), a Wash buffer, pH = 8.0 (Dako), and a Tris buffer, pH = 5.0 (Sigma). S
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br Acknowledgments br Introduction Thermal air
2018-11-09
Acknowledgments Introduction Thermal air convection in closed and tilted rectangular cavities is of interest due to the fact that containers of this type are the elements in a great number of technical devices. Their orientation can change smoothly or stepwise, while the convective flows in th
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However until now combined influence on SAV of H
2018-11-09
However, until now combined influence on SAV of H and other light elements such as C, O and N as well as trapping of H atoms by the monovacancy in the Ti lattice were poorly studied. At the same time the possibility of such influence is indicated by experimental data on Al lattice with C and H impur
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Currently much developmental neuroimaging work on cognitive
2018-11-09
Currently, much developmental neuroimaging work on cognitive control has been done using working memory tasks. A recent met-analysis of this literature documented bilateral dlPFC (BA6) activity to significantly increase with age during working memory (Andre et al., 2016). Moreover, from a theoretica
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Using a wide array of histological and electrophysiological
2018-11-09
Using a wide array of histological and electrophysiological experimental approaches, these data clearly support a mechanistic role of neuronal Monastrol in the intrinsic epileptogenicity of human HH and strenghten the cellular model in which HH neuron clusters of spontaneously firing interneurons p
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ML 786 dihydrochloride Cities across Europe are already expe
2018-11-09
Cities across Europe are already experiencing an increase in ZIKV importations via travellers from the Americas (Maria et al., 2016; Zammarchi et al., 2015). Two recent studies assessed the risk of transmission of ZIKV in Europe reaching contrasting conclusions (Guzzetta et al., 2016; WHO, 2016). On
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br Funding Sources This work
2018-11-09
Funding Sources This work was supported by Cancer Research UK (C1094/A11728 to CMLW and NGB for the RAPPER study, C26900/A8740 to GCB, and C8197/A10865 to AMD), the Royal College of Radiologists (C26900/A8740 to GCB), the National Institute for Health Research (GCB; no grant number), Addenbrooke\
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Finally we sequenced the DNA
2018-11-09
Finally, we sequenced the DNA extracted from the white-blood Special Health Care Needs (WBC) of 39 cfDNA TP53-positive patients, from which material was available (19 cases and 20 controls). Five cfDNA TP53 mutations (from one case and four controls) were detected in the WBC DNA, with similar AFs to
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