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br Discussion There were recurrences out
2019-05-22
Discussion There were 2 recurrences (8.3%¸ 2 out of 24 patients), 1 of which occurred immediately following the procedure. In this patient, SVT was not induced with programmed atrial or ventricular stimulations after the ablation of accessory pathway. Ventriculoatrial conduction was through the A
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Education and lifestyle changes for
2019-05-22
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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br Epigenetic regulation of genes involved in hepatic lipid
2019-05-22
Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl
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In their analysis the investigators did not include
2019-05-22
In their analysis, the investigators did not include common causes of CKD in sub-Saharan Africa other than HIV, diabetes, and hypertension—notable omissions were chronic glomerulonephritis and use of herbal or traditional treatments. Also, communicable diseases might contribute substantially to CKD
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Paying now rather than forever
2019-05-22
Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Despite impressive progress towards elimination social unres
2019-05-22
Despite impressive progress towards elimination, social unrest, gaps in the coverage of populations at risk, competing health interests, and possible donor fatigue present challenges to successful elimination of human African trypanosomiasis caused by and subsequent maintenance of this status. The t
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Introduction Multiple myeloma MM is the
2019-05-22
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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During the ACh provocation test our
2019-05-22
During the ACh provocation test, our patient did not complain of chest pain, ECG showed no discernible ST-T changes, and CAG demonstrated no spastic findings. These indicate that ACh evoked the J wave by its direct pharmacological actions in this case. J waves are currently recognized as a surface E
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br Prognosis The management of AML in the
2019-05-21
Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old
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Visto el franquismo como el gran eje de la
2019-05-21
Visto el franquismo como el gran eje de la discordia, el punto de in flexión se produjo en 1949 con motivo de la presentación en la onu de una propuesta conjunta de cuatro países de América Latina: Brasil, Bolivia, Colombia y Perú. La propuesta de resolución del cuatripartito latinoamericano (proyec
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br Material and methods br Results br Discussion ES SCLC
2019-05-21
Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of
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br Clinical characteristics Brugada syndrome is
2019-05-21
Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn
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Letsas et al reported that the prevalence of Brugada
2019-05-21
Letsas et al. reported that the prevalence of Brugada-type ECG was 0.34% in men and 0.04% in women in the Greek population [19]. Despite the similar BS gender differences between the Greeks and the Japanese, many multicenter studies performed in Western countries indicated that the frequency of men
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Education and lifestyle changes for
2019-05-21
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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FGF is a member of the FGF family It is
2019-05-21
FGF21 is a member of the FGF family. It is preferentially expressed in the liver and is inducible in adipose tissue. As an insulin-sensitizing metabolic regulator, it stimulates methysergide uptake by adipocytes and also targets the central nervous system. FGF21 treatment corrects diet-induced obes
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