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br Author contributions br Declaration of interests
2018-10-30
Author contributions Declaration of interests Acknowledgements This publication made use of the Neisseria Multi Locus Sequence Typing website (http://pubmlst.org/neisseria/) developed by Keith Jolley and sited at the University of Oxford (Jolley and Maiden, 2010). The development of this
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Controlling the immune dysfunctions and overcoming the short
2018-10-30
Controlling the immune dysfunctions and overcoming the shortage of islet β jnk inhibitors are two critical steps for the treatment of T1D. Conventional immunotherapies (e.g., CD3 and CD20 mAb treatments) targeting the general immune cell compartment usually leads to the absolute decline of cell num
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Restriction of conditionally essential amino acids in the di
2018-10-30
Restriction of conditionally essential amino acids in the diet could also impact health. Arginine serves as a precursor for the synthesis of nitric oxide, creatine, symmetric and asymmetric dimethylarginine, and polyamines, and is interconvertible with proline and glutamate (Wu, 2009). Glutamine is
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br Author contributions br Conflicts of Interest
2018-10-30
Author contributions Conflicts of Interest Introduction With 15 million units transfused per year, red blood cell (RBC) transfusion is the most common procedure performed in United States hospitals (Pfuntner et al., 2013). Exposure to numerous foreign non-ABO RBC antigens during transfusion
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A potential limitation of our study was the use
2018-10-30
A potential limitation of our study was the use of hospital controls as proxies of healthy people. Controls were admitted for a wide variety of routine conditions unrelated to tobacco and it is implausible that a high proportion of the controls with a detectable damaging TP53 mutation developed a ca
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Despite a clear oncogenic role
2018-10-29
Despite a clear oncogenic role for NFIB in SCLC and melanoma, tumour suppressive functions have been demonstrated or strongly suggested in other cancers. Although the molecular mechanisms behind its anti-oncogenic functions are not well understood, the fact that NFIB is widely expressed in multiple
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br Experimental design materials and
2018-10-29
Experimental design, materials and methods Conflict of interest Acknowledgment We wish to thank the Academy of Finland (Center of Excellence in Biomembrane Research, project no. 2721130), and the European Research Council (Advanced Grant project CROWDED-PRO-LIPIDS) for financial support. Fo
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br Experimental design materials and methods br Acknowledgme
2018-10-29
Experimental design, materials and methods Acknowledgments We are grateful for funding from ESRC under Grant reference no ES/K004824/1. We are also grateful for the services of the Secure Data Service support team. Specifications Table Value of the data Data The dataset consists of cross
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As a model of prenatal adversity we chose maternal cigarette
2018-10-29
As a model of prenatal adversity, we chose maternal cigarette smoking during pregnancy (MSP). This choice reflects high prevalence of MSP in the general population; the latest results of the National Survey on Drug Use and Health (U.S.A.) suggest that smoking during pregnancy has not changed signifi
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br Study chasing versus inanimate motion br
2018-10-29
Study 1: chasing versus inanimate motion Study 2: chasing versus random General discussion Both studies postulate evidence of a strong positive amplitude for the chasing agent in the low occipital and post temporal areas 400ms post hydroxylase inhibitor onset. Given that prior research exa
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Many risk factors may lead to disrupted
2018-10-29
Many risk factors may lead to disrupted language development (Bishop et al., 2003; Rice, 2012; Zubrick et al., 2007). One predictor drawing attention is early receptive language skill. Evidence suggests that hcv protease inhibitors the receptive language status of a late-talking child is predictive
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br Conflict of interest br
2018-10-29
Conflict of interest Acknowledgements The authors kindly thank Dr. Pietro Scatturin for laboratory technical support and Dr. Laura Babcock for English manuscript proof-reading. A special thank goes also to all children and their families for participating to the study. This work was supported
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br Discussion Cutaneous metastases occur in
2018-10-29
Discussion Cutaneous metastases occur in 0.7–9.0% of all patients with various kinds of malignancies such as visceral cancer, leukemia, lymphoma, and melanoma. In a retrospective study of 4020 patients with metastatic disease, the origins of common cutaneous metastases in women were the breast, c
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Es interesante notar que el
2018-10-29
Es interesante notar que el consumo en este caso es una forma de elusión. En vez de los contactos que Guillermo desearía tener, ve porno. Antepone el control SAR 405 su deseo. Cuando puede irse a dormir tarde, porque no trabaja al otro día, entonces madruga viendo porno. Trabajo – porno – masturbaci
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Real exchange rate is positively significant only in
2018-10-29
Real exchange rate is positively significant only in case of China and it has no effect on FPI volatility in case of remaining three countries. China is not trading in primary goods so fluctuation in exchange rate does not exist, so RER has significant positive effect on portfolio investment volatil
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